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Title: SERUM LEPTIN AND SOME MINERALS CONCENTRATIONS IN CORD BLOOD: RELATIONSHIP TO BIRTH WEIGHT
Author(s): USAMA R. EL-Safy , Mervat A. Hesham , Hanan A. Abd El-Rahman , Somia H. Abd-Alla, Mohammad A. Abd EL-Hady
Source: The Egyptian Journal of Neonatology, 2001, Vol. 2, No. 1,,

Abstract: Leptin is a hormone secreted by adipocytes. It regulates body weight and its levels correlate with body fat content. Also, optimal mineral intake is crucial, especially during the period of rapid growth that occurs during infancy and childhood. So this work was done to study the levels and effects of leptin and some minerals (calcium, phosphorous, zinc and copper) on foetal growth and to evaluate their relationship to birth weight .This study conducted on sixty neonates immediately after birth and they were categorized into 4 groups :appropriate for gestational age (FT-AGA) , full term large for gestational age (F.T. – LGA) , full term small for gestational age(FT-SGA) , preterm appropriate for gestational age (Pre-AGA). All groups were subjected to full maternal history and thorough clinical examination , anthropometeric measurements and laboratory investigations for measurements of serum levels of leptin by Immunoradiometric assay and minerals (calcium – phosphorus – zinc -copper )by plasma emmission spectrometer. Our results showed highly significant differences between the four studied groups as regard leptin concentrations. FT-LGA group had higher leptin level than FT-AGA and FT-SGA while the preterm had the lowest level ...

Addresses: Pediatric and Clinical Biochemistry Departments Faculty of Medicine - Zagazig University..

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Country Code: EG