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Title: Acinic cell carcinoma of the salivary glands: a literature review. DF
Author(s): Nabil Al-Zaher, Amani Obeid, Suhail Al-Salam, Bassam Sulaiman Al-Kayyali
Source: Hematology - Oncology and Stem Cell Therapy , 2009 , 2 , 1, 259-264

Abstract: Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the preddominant site of origin and women are usually more frequently diagnosed than men. Previous radiation exposure and familial predisposition are some of the risk factors for ACC. A slowly enlarging mass lesion in the tail of the parotid gland is the most frequent presentation. The diagnosis is usually confirmed with a fine needle aspiration biopsy, and surgical excision is the main treatment of this malignant neoplasm. Other treatment modalities such as radiotherapy may be indicated in some cases. ACC has a significant tendency to recur, to produce metastases (cervical lymph nodes and lungs), and may have an aggressive evolution. Therefore, long-term follow-up is mandatory after treatment...

Addresses: aDepartment of Otolaryngology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia, bFRCPath, University of the United Arab Emirates, Al Ain, United Arab Emirates, and cTawam Johns Hopkins Hospital, Al Ain, United Arab Emirates..

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Country Code: SA