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Title: Assessment of the Pattern of Regional Cerebral Blood Flow in Down Syndrome Using Brain Single Photon Emission Computed Tomography
Author(s): Rabah M. Shawky, Eman A. Zaky, Laila F. Matta, Alia M. El-Shoubary, Ibrahim M. Abdou.
Source: Egyptian Journal of Medical Human Genetics, 2000, Vol. 1, No. 1,, 35-53

Abstract: This study was conducted to assess the pattern of regional cerebral blood flow (rCBF) in Down syndrome subjects using brain single photon emission computed tomography (SPECT) and to correlate the recorded SPECT findings with the neurological and behavioral manifestations and cognitive and linguistic abilities of the studied cases. To fulfil the aim of the study, 17 cases with Down syndrome without congenital heart diseases were enrolled. They were 13 males and 4 females. Their ages ranged between 7 mo and 22 yrs. Full medical history taking, thorough clinical examination, IQ assessment, mental age and language age delays estimation, associated behavior and or psychiatric disorder diagnosis and assessment of the pattern of regional cerebral blood flow both quantitatively and qualitatively using brain SPECT were performed for all studied cases. Furthermore, cranial CT was done for patients with suspected intracranial structural abnormalities...

Addresses: Pediatric Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Radiotherapy and Nuclear Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Phoniatric Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt...

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Country Code: EG